Thorne Research, 5-MTHF, 1 mg, 60 Capsules – Active folate

(91 customer reviews)

$85.38 $73.43

2 in stock

SKU: 153401895821 Category:


Thorne Research, 5-MTHF, 1 mg, 60 Capsules


·         Methylfolate

·         Dietary Supplement

·         Foundational

·         Mood

·         Heart/Vessels

·         Gluten-Free

Active folate for mood, heart health, fetal development, and nerve support.

5-MTHF is an active, tissue-ready form of folate. It’s an essential B vitamin that supports methylation. Many individuals don’t get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic makeup.

Many individuals don’t get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects, which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin, melatonin, dopamine, epinephrine, and norepinephrine, supplementation supports healthy mood.

Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner.

It is important for a woman of childbearing age to get enough folic acid – not just those women who are planning to become pregnant. Because half of pregnancies are unplanned, any woman who could become pregnant should get enough folic acid every day. Folic acid intake is especially important before conception and during early pregnancy since its biggest need is during the first trimester – when a woman might not even know she is pregnant. Supplementation with the active form of folic acid – 5-MTHF (L-5 Methyltetrahydrofolate)– is always preferable.

Acting with vitamin B12, 5-MTHF functions as a methyl-group donor, thereby facilitating the conversion of the amino acid homocysteine to methionine. An elevated homocysteine level is a risk factor for a number of undesirable health conditions. Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.

Suggested Use

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Other Ingredients

Microcrystalline cellulose, hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.


Tamper Evident: Use only if bottle is sealed. Store tightly sealed in a cool, dry place.

If pregnant, consult your health-care practitioner before using this product.

Supplement Facts
Serving Size: One Capsule
One Capsule Contains: % Daily Value
Folate (1 mg as 
1.7 mg DFE 425%
Daily Value (DV)
† This product uses Gnosis S.p.A.’s L-5-Methyltetrahydrofolate (Extrafolate-S).


As with any dietary supplement, please inform your healthcare professional before taking

products are not intended to diagnose, treat, cure or prevent any disease. We do not manufacture the goods sold and rely totally on the accuracy of the information given by the supplier/manufacturer. We cannot give medical opinions

While we strive to ensure the accuracy of the product images and information,  some manufacturing changes to packaging and/or ingredients  maybe pending  an update  

 items may occasionally ship with alternate packaging,

 We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided on our listing

Additional information


Thorne Research



Expiry Date

June 2020



91 reviews for Thorne Research, 5-MTHF, 1 mg, 60 Capsules – Active folate

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